Welcome To Chemohelp

Types of Chemotherapy:

Alkylating Agents

Alkylating antineoplastic agent adds alkyl groups to the DNA base pairs which permanently damages the DNA and stop the growth of tumour by restricting the division of DNA.The cells which are modified by this agent are not destroyed but they cannot grow further

Antimetabolites

Antimetabolites are the agents used to stop metabolites, metabolites is a term used for organic compounds synthesized, recycled or broken down in cells.Antimetabolites are similar to the structure of the metabolites but cannot be used by the body like the metablites, they are present as a decoy to rectrict the vital function of a cell and the cell are unable to grow and survive.So the antimetabolites are used for the treatment of the cancer.

Plant Alkaloids

As there name suggests, these are the organic derivatives of plants used in cancer treatment.They are cell cycle specific agents and the cycles affected by them are varies from the drug to drug.They also inhibits mitosis, cause disassembly or damage to the microtubules etc

Anthracyclines

Anthracyclines are the class of drugs which are derived from the streptomyces bacteria used in cure for cancer and also used as a antibiotic.They are the most effective drugs against the cancer among all the drugs.They manipulates the DNA minor grooves and they cause free radical damages to the ribode structure in the cell.They are frequently in used in leukemia therapy.

Topisomerase inhibitors

Topoisomease inhibitors are the agents used to interfere the function of topoisomerase.Topoisomerase are the enzymes which are responsible for the control the changes in the DNA molecule by catalyzing, breaking and rejoining the bonds of the DNA structure.Inhibitors blocks the function of topoisomerase and so the growth of cell affected by the topoisomerase inhibitors

Other antitumour agents

Angiogenesis Inhibitors, DNA Synthesis Inhibitors, DNA-RNA Transcription Regulators, Gene Regulation etc.